Blantyre United have only managed to bag 12 points from 20 games and are yet to score in the second the second round.
Dwangwa United and Chitipa United are equally in the relegation zone with the latter anchoring the log table with 11 points from 19 games.
Mtetemera said he will do everything possible to turn turn tables and help the team jump out of the relegation zone.
"We will not give up. Will fight on until the final game and I know will play our game. We will have to polish up some areas, mainly the striking force.
"It's very pathetic not to score a goal in five successive matches. However, we have more games to play and by the end of the campaign, we will have moved out of the relegation zone," said Mtetemera.
On their next assignment against third-placed Nyasa Big Bullets, Mtetemera said "it will be a tough match, but we will equally come hard on them".
Meanwhile, Wizards FC, who are equally struggling, have fired their head coach Trevor Kajawa for poor performance.
Goalkeepers trainer Simeon Kapuza is now the caretaker coach and is faced with triky assignment against Mzuni FC at Chiwembe in Blantyre.
Elsewhere, Silver Strikers hope to reduce the gap when host league leaders Mighty Be Forward Wanderers at Silver Stadium on Saturday.
Silver, widely known as the Bankers, have got 39 points from 19 games while Wanderers, who also battle it out Blue Eagles at Nankhaka Stadium on Sunday, have got 44 points from 18 games.
Red Lions will host Civil Sporting at Balaka Stadium while Dwangwa United and Chitipa United will lockhorns at Chitowe Stadium in Nkhotakota.
And Sunday, Mafco F.C will Chitipa United at Chitowe Stadium; Azam Tigers and Mzuni F.C will battle it out at MDC Stadium; Moyale will host their brothers in arms Kamuzu Barracks at Mzuzu Stadium with Blue Eagles facing off with Wanderers at Nankhaka Stadium.